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  Indian J Med Microbiol
 

Figure 2: Bone marrow tissue using hematoxylin and eosin stain. The upper panel (a) demonstrates diffuse replacement by ovoid histiocytes with abundant, finely fibrillar, pale blue gray cytoplasm that is crinkled or wrinkled paper-like and the lower (×100) and panel (b) demonstrates Gaucher cells are typically enlarged, with eccentric nuclei, condensed chromatin and cytoplasm with a heterogeneous “crumpled tissue paper” appearance (×100) cropped and enlarged

Figure 2: Bone marrow tissue using hematoxylin and eosin stain. The upper panel (a) demonstrates diffuse replacement by ovoid histiocytes with abundant, finely fibrillar, pale blue gray cytoplasm that is crinkled or wrinkled paper-like and the lower (×100) and panel (b) demonstrates Gaucher cells are typically enlarged, with eccentric nuclei, condensed chromatin and cytoplasm with a heterogeneous “crumpled tissue paper” appearance (×100) cropped and enlarged