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CLINICAL VIGNETTE
Year : 2019  |  Volume : 11  |  Issue : 1  |  Page : 38-40

Filamentous rods in the cerebrospinal fluid of a child with ventriculoperitoneal shunt: “Separation Anxiety” at the microscopic level!


1 Department of Pathology and Laboratory Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA
2 Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA
3 Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital and The Ohio State University, Columbus, Ohio, USA

Correspondence Address:
Dr. Samir B Kahwash
Nationwide Children's Hospital, 700 Childrens Drive, Columbus, Ohio 43205
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmbs.ijmbs_76_18

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Certain bacteria and antibiotic combinations can result in unusual morphologic transformations such as the creation of septate filamentous bacterial rods, where division is preserved, but separation is inhibited. This is often seen when subinhibitory concentrations of antibiotics are administered. Herein, we describe this phenomenon in the case of a teenage boy with an infected ventriculoperitoneal shunt, whose culture-proven Pseudomonas aeruginosa took on a filamentous appearance following antibiotic treatment. This transformation is important to recognize, so it is not misconstrued as fungal hyphae, committing the patient to unnecessary treatment.


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