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CASE REPORT
Year : 2018  |  Volume : 10  |  Issue : 2  |  Page : 68-70

Renal replacement therapy for metformin and sitagliptin overdose


1 Department of Nephrology, Tawam Hospital, A Ain, Abu Dhabi, United Arab Emirates
2 Department of Pharmacy, Tawam Hospital, A Ain, Abu Dhabi, United Arab Emirates
3 Department of Endocrinology, Tawam Hospital, A Ain, Abu Dhabi, United Arab Emirates

Correspondence Address:
Dr. Nicole Gebran
Department of Pharmacy, Tawam Hospital, PO Box 15258, Al-Ain, Abu Dhabi
United Arab Emirates
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmbs.ijmbs_72_17

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Metformin and sitagliptin are widely used in the management of type 2 diabetes mellitus. We present a case who reported ingestion of an overdose of metformin and sitagliptin in a suicidal attempt. The patient presented with severe lactic acidosis, hypotension, and hyperglycemic acute kidney injury, successfully treated medically with intravenous infusion of fluids and sodium bicarbonate, and prompt convection hemodialysis.


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