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Year : 2015  |  Volume : 7  |  Issue : 5  |  Page : 180-183

Colchicine poisoning: A case of deliberate self poisoning, late presentation and fatal outcome

1 Department of Medicine, Faculty of Medicine, University of Zawia, Libya
2 Medical Department, Zawia Teaching Hospital, Zawia, Libya
3 Intensive Care Unit, Zawia Teaching Hospital, Zawia, Libya

Correspondence Address:
Elham A Draa
Department of Medicine, Faculty of Medicine, University of Zawia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1947-489X.210285

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Colchicine poisoning is relatively uncommon, but potentially life threatening event due to the high toxicity of the drug and ability to precipitate severe multi-organ failure in overdose. Colchicine is used primarily in the treatment of acute attacks of gout and inflammatory diseases. We report a the first case of a 18 -year-old Libyan female who presented to the emergency department approximately 20-28 hours after ingesting 30 mg of colchicine in a suicide attempt. In spite of gastric lavage, use of activated charcoal and supportive measures, multi-organ system failure developed over the following two days, and patient died on the third day after admission. Salient toxicological and clinical aspects of colchicine poisoning are discussed.

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