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  Indian J Med Microbiol
 

Figure 4: The parallel metabolic pathways of n-6 and n-3 polyunsaturated fatty acids. The series of alternating desaturation and elongation reactions in both pathways are catalyzed by the same enzymes. The two pathways compete for the same rate-limiting Δ6-desaturase. AA: Arachidonic acid (20:4; n-6); ALA: Alpha-linolenic acid (18:3; n-3), DGLA: Dihomo-gamma-linolenic acid (20:3; n-6), DHA: Docosahexaenoic acid (22:6; n-3), EPA: Eicosapentaenoic acid (20:5; n-3); GLA: Gamma-linolenic acid (18:3; n-6); LA: Linoleic acid (18:2; n-6). Adrenic acid (22:4; n-6) is found in significant amounts in the phospholipids of the adrenal glands and testes

Figure 4: The parallel metabolic pathways of <i>n</i>-6 and <i>n</i>-3 polyunsaturated fatty acids. The series of alternating desaturation and elongation reactions in both pathways are catalyzed by the same enzymes. The two pathways compete for the same rate-limiting Δ6-desaturase. AA: Arachidonic acid (20:4; <i>n</i>-6); ALA: Alpha-linolenic acid (18:3; <i>n</i>-3), DGLA: Dihomo-gamma-linolenic acid (20:3; <i>n</i>-6), DHA: Docosahexaenoic acid (22:6; <i>n</i>-3), EPA: Eicosapentaenoic acid (20:5; <i>n</i>-3); GLA: Gamma-linolenic acid (18:3; <i>n</i>-6); LA: Linoleic acid (18:2; <i>n</i>-6). Adrenic acid (22:4; <i>n</i>-6) is found in significant amounts in the phospholipids of the adrenal glands and testes