Ibnosina Journal of Medicine and Biomedical Sciences

REVIEW ARTICLE
Year
: 2018  |  Volume : 10  |  Issue : 1  |  Page : 3--8

The dietary fat–heart disease hypothesis: An ongoing debate


Nasr Anaizi 
 Department of Physiology, Faculty of Medicine, University of Benghazi, Benghazi, Libya

Correspondence Address:
Prof. Nasr Anaizi
Department of Physiology, Faculty of Medicine, University of Benghazi, Benghazi
Libya

The belief that the consumption of saturated fat as the primary source of daily energy needs is detrimental to heart health has held a firm grip on public consciousness for decades. It was initially based entirely on tenuous observational (correlation) studies but was later bolstered by a vast array of evidence and more direct observations from long-term randomized controlled trials and dietary intervention studies. Further support also came from the elucidation of the pathophysiology and molecular mechanisms involved in atherogenesis. However, in recent years, the association between dietary saturated fat and heart disease has come under attack based mainly on meta-analyses and large multinational studies most of which relying on questionnaires and diet recall. More recent publications have elevated the debate to a new level, leading some experts to question the evidence behind commonly accepted dietary recommendations, attracting media attention, and generating heated debates. Here, the most relevant studies will be reviewed defining the salient issues and where the proponents and opponents of the hypothesis stand.


How to cite this article:
Anaizi N. The dietary fat–heart disease hypothesis: An ongoing debate.Ibnosina J Med Biomed Sci 2018;10:3-8


How to cite this URL:
Anaizi N. The dietary fat–heart disease hypothesis: An ongoing debate. Ibnosina J Med Biomed Sci [serial online] 2018 [cited 2020 Jan 27 ];10:3-8
Available from: http://www.ijmbs.org/article.asp?issn=1947-489X;year=2018;volume=10;issue=1;spage=3;epage=8;aulast=Anaizi;type=0