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Year : 2016  |  Volume : 8  |  Issue : 1  |  Page : 3-14

Measuring obesity: Fat or fit!

Department of Physiology, Faculty of Medicine, University of Benghazi, Benghazi, Libya

Correspondence Address:
Nasr Anaizi
Department of Physiology, Faculty of Medicine, University of Benghazi, Benghazi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1947-489X.210213

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Obesity is widely recognized as a major global health challenge because of its strong association with multiple cardiometabolic risk factors including diabetes, hypertension, and coronary artery disease. It compromises the quality of life and shortens life expectancy. This minireview discusses firstly the physiological mechanisms involved in energy homeostasis including peptidergic signalling of hunger and satiety from the GI tract mediated by the gut hormones (ghrelin, CCK, PYY, GIP, GLP-1,), and the status of energy stores from the adipose tissue mediated primarily by leptin, secondly, the field methods used in clinical practice to estimate the degree of obesity and lastly, management of the obese patient.

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